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Latest workflows useful for pinpointing the MOA of novel compounds usually involve an variety of useful screening assays incorporating a myriad of isolated biological targets. These methods frequently do not history purpose from the dynamic surroundings by which these targets commonly reside. This is especially significant for ion channel targets t
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We also collected information about notices of FDA regulatory actions accessible with the Federal Register22 as well as therapeutic course in the WHO Anatomical Therapeutic Chemical Classification System23 (Supplemental Desk S1). We classified the medicines using the anatomical primary team. We selected the therapeutic subgroup for systemic anti-in